Nanomechanical In Situ Monitoring of Proteolysis of Peptide by Cathepsin B

Characterization and control of proteolysis of peptides by specific cellular protease is a priori requisite for effective drug discovery. Here, we report the nanomechanical, in situ monitoring of proteolysis of peptide chain attributed to protease (Cathepsin B) by using a resonant nanomechanical mic...

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Detalhes bibliográficos
Main Authors: Kwon, Taeyun, Park, Jinsung, Yang, Jaemoon, Yoon, Dae Sung, Na, Sungsoo, Kim, Chang-Wan, Suh, Jin-Suck, Huh, Yong-Min, Haam, Seungjoo, Eom, Kilho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707113/
https://ncbi.nlm.nih.gov/pubmed/19606222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006248
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