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Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin

The ubiquitin-proteasome pathway plays an important role in DNA damage signaling and repair by facilitating the recruitment and activation of DNA repair factors and signaling proteins at sites of damaged chromatin. Proteasome activity is generally not thought to be required for activation of apical...

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Detalhes bibliográficos
Main Authors: Sakasai, Ryo, Teraoka, Hirobumi, Tibbetts, Randal S
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818427/
https://ncbi.nlm.nih.gov/pubmed/19959400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.10.008
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