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Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo

Recent evidence suggests that abnormal activation of cyclin-dependent kinase 5 (cdk5) is a critical prodeath signal in stroke. However, the mechanism(s) by which cdk5 promotes death is unclear. Complicating the role of cdk5 are the observations that cdk5 can exist in multiple cellular regions and po...

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Autors principals: Rashidian, Juliet, Rousseaux, Maxime W., Venderova, Katerina, Qu, Dianbo, Callaghan, Steve M., Phillips, Maryam, Bland, Ross J., During, Matthew J., Mao, Zixu, Slack, Ruth S., Park, David S.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818426/
https://ncbi.nlm.nih.gov/pubmed/19812325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3892-09.2009
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