Effect of Pioglitazone on Survival and Renal Function in a Mouse Model of Polycystic Kidney Disease

BACKGROUND/AIMS: Cystic epithelia in polycystic kidney disease display features similar to malignant cells. Thiazolidinediones have been shown to have anti-neoplastic properties, therefore we tested the hypothesis that pioglitazone reduces cyst formation, improves renal function, and prolongs surviv...

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Detalhes bibliográficos
Main Authors: Raphael, K.L., Strait, K.A., Stricklett, P.K., Baird, B.C., Piontek, K., Germino, G.G., Kohan, D.E.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Original Report: Laboratory Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818398/
https://ncbi.nlm.nih.gov/pubmed/19776560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000242432
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