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Drug repurposing in autosomal dominant polycystic kidney disease: back to the future with pioglitazone

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of end-stage kidney failure. At present, only one drug, tolvaptan, has been approved for use to slow disease progression, but its use is limited by reduced tolerability and idiosyncratic liver toxicity. Thiazolid...

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Bibliografische gegevens
Gepubliceerd in:Clin Kidney J
Hoofdauteurs: Mao, Zhiguo, Valluru, Manoj K, Ong, Albert C M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243263/
https://ncbi.nlm.nih.gov/pubmed/34221378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfab062
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