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Antimalarial Activity of Azadipeptide Nitriles

Azadipeptide nitriles – novel cysteine protease inhibitors – display structure-dependent antimalarial activity against both chloroquine-sensitive and chloroquine-resistant lines of cultured Plasmodium falciparum malaria parasites. Inhibition of parasite’s haemoglobin-degrading cysteine proteases was...

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Main Authors: Löser, Reik, Gut, Jiri, Rosenthal, Philip J., Frizler, Maxim, Gütschow, Michael, Andrews, Katherine T.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818362/
https://ncbi.nlm.nih.gov/pubmed/19913414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.10.122
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