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Syntheses and antibacterial activity studies of new oxazolidinones from nitroso Diels–Alder chemistry

A series of novel oxazolidinone antibiotics having [2.2.1] and [2.2.2] bicyclic oxazine moieties at the C-5 side chain of the A ring was synthesized by nitroso Diels–Alder reactions, from three linezolid analogs containing morpholine, piperazine and thiomorpholine, respectively, as the C-ring compon...

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Autors principals: Yan, Shanshan, Miller, Marvin J., Wencewicz, Timothy A., Möllmann, Ute
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818252/
https://ncbi.nlm.nih.gov/pubmed/20031407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.10.018
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