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Preparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels–Alder reactions
A series of 10,13-disubstituted 16-membered macrolides was synthesized using nitroso Diels–Alder reactions of leucomycin A7. Despite the extensive constituent functionalities in leucomycin, the hetero cycloaddition reactions proceeded in a highly regio- and stereoselective fashion. Subsequent chemic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058769/ https://ncbi.nlm.nih.gov/pubmed/20090988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b922450e |
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