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Degradation of an intramitochondrial protein by the cytosolic proteasome

Mitochondrial uncoupling protein 2 (UCP2) is implicated in a wide range of pathophysiological processes, including immunity and diabetes mellitus, but its rapid degradation remains uncharacterized. Using pharmacological proteasome inhibitors, immunoprecipitation, dominant negative ubiqbiquitiuitin m...

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Bibliografiska uppgifter
Huvudupphovsmän: Azzu, Vian, Brand, Martin D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818195/
https://ncbi.nlm.nih.gov/pubmed/20103532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.060004
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