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Degradation of an intramitochondrial protein by the cytosolic proteasome
Mitochondrial uncoupling protein 2 (UCP2) is implicated in a wide range of pathophysiological processes, including immunity and diabetes mellitus, but its rapid degradation remains uncharacterized. Using pharmacological proteasome inhibitors, immunoprecipitation, dominant negative ubiqbiquitiuitin m...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818195/ https://ncbi.nlm.nih.gov/pubmed/20103532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.060004 |
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