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Allosteric communication between protomers of dopamine Class A GPCR dimers modulates activation

A major obstacle to understanding the functional importance of dimerization between Class A G protein-coupled receptors (GPCRs) has been the methodological limitation in achieving control of the identity of the components comprising the signaling unit. We have developed a functional complementation...

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Autori principali: Han, Yang, Moreira, Irina S., Urizar, Eneko, Weinstein, Harel, Javitch, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817978/
https://ncbi.nlm.nih.gov/pubmed/19648932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.199
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