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Integrated Multi-Class Classification and Prediction of GPCR Allosteric Modulators by Machine Learning Intelligence

G-protein-coupled receptors (GPCRs) are the largest and most diverse group of cell surface receptors that respond to various extracellular signals. The allosteric modulation of GPCRs has emerged in recent years as a promising approach for developing target-selective therapies. Moreover, the discover...

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Pubblicato in:Biomolecules
Autori principali: Hou, Tianling, Bian, Yuemin, McGuire, Terence, Xie, Xiang-Qun
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230833/
https://ncbi.nlm.nih.gov/pubmed/34208096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060870
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