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Developmental Programming: Impact of Prenatal Testosterone Excess and Postnatal Weight Gain on Insulin Sensitivity Index and Transfer of Traits to Offspring of Overweight Females

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women and is exacerbated by obesity. Exposure of ewes to excess testosterone (T) from d 30–90 of gestation culminates in anovulation, functional hyperandrogenism, LH excess, and polyfollicular ovaries, features s...

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Detalhes bibliográficos
Main Authors: Padmanabhan, V., Veiga-Lopez, A., Abbott, D. H., Recabarren, S. E., Herkimer, C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817622/
https://ncbi.nlm.nih.gov/pubmed/19966179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1015
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