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Developmental Programming: Prenatal and Postnatal Contribution of Androgens and Insulin in the Reprogramming of Estradiol Positive Feedback Disruptions in Prenatal Testosterone-Treated Sheep

Prenatal testosterone (T) excess compromises the estradiol (E(2)) positive feedback. This study tested the hypothesis that antagonizing androgen action or improving insulin sensitivity prenatally would prevent positive feedback disruptions from developing, whereas postnatal intervention with androge...

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Detalhes bibliográficos
Main Authors: Abi Salloum, Bachir, Herkimer, Carol, Lee, James S., Veiga-Lopez, Almudena, Padmanabhan, Vasantha
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359592/
https://ncbi.nlm.nih.gov/pubmed/22454153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-2074
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