Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products.
The rat neu oncogene encodes a cell surface glycoprotein, p185, that possesses tyrosine kinase activity. The p185 polypeptide exhibits structural similarity to the epidermal growth factor receptor (EGFR) at both the deduced amino acid and nucleic acid level. However, the neu oncogene and the gene en...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2899889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5389 |
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