Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products.

The rat neu oncogene encodes a cell surface glycoprotein, p185, that possesses tyrosine kinase activity. The p185 polypeptide exhibits structural similarity to the epidermal growth factor receptor (EGFR) at both the deduced amino acid and nucleic acid level. However, the neu oncogene and the gene en...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kokai, Y, Dobashi, K, Weiner, D B, Myers, J N, Nowell, P C, Greene, M I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2899889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5389
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