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Similarly Strong Purifying Selection Acts on Human Disease Genes of All Evolutionary Ages

A number of studies have showed that recently created genes differ from the genes created in deep evolutionary past in many aspects. Here, we determined the age of emergence and propensity for gene loss (PGL) of all human protein–coding genes and compared disease genes with non-disease genes in term...

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Detalhes bibliográficos
Main Authors: Cai, James J., Borenstein, Elhanan, Chen, Rong, Petrov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817408/
https://ncbi.nlm.nih.gov/pubmed/20333184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evp013
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