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Osteoblasts and Bone Marrow Mesenchymal Stromal Cells Control Hematopoietic Stem Cell Migration and Proliferation in 3D In Vitro Model
BACKGROUND: Migration, proliferation, and differentiation of hematopoietic stem cells (HSCs) are dependent upon a complex three-dimensional (3D) bone marrow microenvironment. Although osteoblasts control the HSC pool, the subendosteal niche is complex and its cellular composition and the role of eac...
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Главные авторы: | , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science
2010
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816998/ https://ncbi.nlm.nih.gov/pubmed/20161704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009093 |
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