PS1/γ-Secretase-Mediated Cadherin Cleavage Induces β-Catenin Nuclear Translocation and Osteogenic Differentiation of Human Bone Marrow Stromal Cells

Bone marrow stromal cells (BMSCs) are considered a promising tool for bone bioengineering. However, the mechanisms controlling osteoblastic commitment are still unclear. Osteogenic differentiation of BMSCs requires the activation of β-catenin signaling, classically known to be regulated by the canon...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Bonfim, Danielle C., Dias, Rhayra B., Fortuna-Costa, Anneliese, Chicaybam, Leonardo, Lopes, Daiana V., Dutra, Hélio S., Borojevic, Radovan, Bonamino, Martin, Mermelstein, Claudia, Rossi, Maria Isabel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178376/
https://ncbi.nlm.nih.gov/pubmed/28053606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3865315
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