IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for trigge...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Suthar, Mehul S., Ma, Daphne Y., Thomas, Sunil, Lund, Jennifer M., Zhang, Nu, Daffis, Stephane, Rudensky, Alexander Y., Bevan, Michael J., Clark, Edward A., Kaja, Murali-Krishna, Diamond, Michael S., Gale, Michael
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816698/
https://ncbi.nlm.nih.gov/pubmed/20140199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000757
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