IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for trigge...

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Bibliografiske detaljer
Main Authors: Suthar, Mehul S., Ma, Daphne Y., Thomas, Sunil, Lund, Jennifer M., Zhang, Nu, Daffis, Stephane, Rudensky, Alexander Y., Bevan, Michael J., Clark, Edward A., Kaja, Murali-Krishna, Diamond, Michael S., Gale, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816698/
https://ncbi.nlm.nih.gov/pubmed/20140199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000757
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