IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for trigge...

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Autores principales: Suthar, Mehul S., Ma, Daphne Y., Thomas, Sunil, Lund, Jennifer M., Zhang, Nu, Daffis, Stephane, Rudensky, Alexander Y., Bevan, Michael J., Clark, Edward A., Kaja, Murali-Krishna, Diamond, Michael S., Gale, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816698/
https://ncbi.nlm.nih.gov/pubmed/20140199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000757
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