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Interaction between Sdo1p and Btn1p in the Saccharomyces cerevisiae model for Batten disease
Juvenile Batten disease is an autosomal recessive pediatric neurodegenerative disorder caused by mutations in the CLN3 gene. The CLN3 protein primarily resides in the lysosomal membrane, but its function is unknown. We demonstrate that CLN3 interacts with SBDS, the protein mutated in Shwachman–Bodia...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2816617/ https://ncbi.nlm.nih.gov/pubmed/20015955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp560 |
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