The Yeast Model for Batten Disease: Mutations in btn1, btn2, and hsp30 Alter pH Homeostasis
The BTN1 gene product of the yeast Saccharomyces cerevisiae is 39% identical and 59% similar to human CLN3, which is associated with the neurodegenerative disorder Batten disease. Furthermore, btn1-Δ strains have an elevated activity of the plasma membrane H(+)-ATPase due to an abnormally high vacuo...
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| Publicado no: | J Bacteriol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11053386/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.22.6418-6423.2000 |
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