The Yeast Model for Batten Disease: Mutations in btn1, btn2, and hsp30 Alter pH Homeostasis

The BTN1 gene product of the yeast Saccharomyces cerevisiae is 39% identical and 59% similar to human CLN3, which is associated with the neurodegenerative disorder Batten disease. Furthermore, btn1-Δ strains have an elevated activity of the plasma membrane H(+)-ATPase due to an abnormally high vacuo...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Bacteriol
Prif Awduron:	Chattopadhyay, Subrata, Muzaffar, Neda E., Sherman, Fred, Pearce, David A.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2000
Pynciau:	Eukaryotic Cells
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11053386/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.22.6418-6423.2000
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