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BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution

BTN1, the yeast homolog to human CLN3 (which is defective in Batten disease), has been implicated in the regulation of vacuolar pH, potentially by modulating vacuolar-type H(+)-ATPase (V-ATPase) activity. However, we report that Btn1p and the V-ATPase complex do not physically interact, suggesting t...

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Autors principals: Padilla-López, Sergio, Langager, Deanna, Chan, Chun-Hung, Pearce, David A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291640/
https://ncbi.nlm.nih.gov/pubmed/22107873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008490
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