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Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex

The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown. The killer immunoglobulin receptor (KIR) gene complex exhibits significant CNV. The evolutionary plasticity of the KIRs and their broad biomedical relevance makes it important to understand how these imm...

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Autores principales: Traherne, James A., Martin, Maureen, Ward, Rosemary, Ohashi, Maki, Pellett, Fawnda, Gladman, Dafna, Middleton, Derek, Carrington, Mary, Trowsdale, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816608/
https://ncbi.nlm.nih.gov/pubmed/19959527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp538
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