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Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex

The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown. The killer immunoglobulin receptor (KIR) gene complex exhibits significant CNV. The evolutionary plasticity of the KIRs and their broad biomedical relevance makes it important to understand how these imm...

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Dettagli Bibliografici
Autori principali: Traherne, James A., Martin, Maureen, Ward, Rosemary, Ohashi, Maki, Pellett, Fawnda, Gladman, Dafna, Middleton, Derek, Carrington, Mary, Trowsdale, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816608/
https://ncbi.nlm.nih.gov/pubmed/19959527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp538
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