Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study

PURPOSE: To analyze the prognostic significance of NPM1 mutations, and the associated gene- and microRNA-expression signatures in older patients with de novo, cytogenetically normal acute myeloid leukemia (CN-AML) treated with intensive chemotherapy. PATIENTS AND METHODS: One hundred forty-eight adu...

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Autori principali: Becker, Heiko, Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Margeson, Dean, Whitman, Susan P., Wu, Yue-Zhong, Schwind, Sebastian, Paschka, Peter, Powell, Bayard L., Carter, Thomas H., Kolitz, Jonathan E., Wetzler, Meir, Carroll, Andrew J., Baer, Maria R., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2010
Soggetti:
Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815994/
https://ncbi.nlm.nih.gov/pubmed/20026798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.1496
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