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Human Triallelic Sites: Evidence for a New Mutational Mechanism?

Most SNPs in the human genome are biallelic; however, there are some sites that are triallelic. We show here that there are approximately twice as many triallelic sites as we would expect by chance. This excess does not appear to be caused by natural selection or mutational hotspots. Instead we prop...

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Hlavní autoři: Hodgkinson, Alan, Eyre-Walker, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815919/
https://ncbi.nlm.nih.gov/pubmed/19884308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.110510
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