MAGUK-Controlled Ubiquitination of CARMA1 Modulates Lymphocyte NF-κB Activity

The adaptor protein CARMA1 is required for antigen receptor-triggered activation of IKK and JNK in lymphocytes. Once activated, the events that subsequently turn off the CARMA1 signalosome are unknown. In this study, we found that antigen receptor-activated CARMA1 underwent lysine 48 (K48) polyubiqu...

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Hauptverfasser: Moreno-García, Miguel E., Sommer, Karen, Shinohara, Hisaaki, Bandaranayake, Ashok D., Kurosaki, Tomohiro, Rawlings, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815576/
https://ncbi.nlm.nih.gov/pubmed/20008554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01129-09
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