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Serine 649 phosphorylation within the PKC-regulated domain down-regulates CARMA1 activity in lymphocytes()
Phosphorylation of CARMA1 is a crucial event initiating the assembly of IKK and JNK signaling complexes downstream of activated antigen receptors. We previously mapped three PKC target sites in murine CARMA1 in vitro, and demonstrated that mutation of two of these serines (S564 and S657) resulted in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433237/ https://ncbi.nlm.nih.gov/pubmed/19917688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902438 |
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