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Telomere Protection by TPP1 Is Mediated by POT1a and POT1b

Mammalian telomeres are protected by the shelterin complex, which contains single-stranded telomeric DNA binding proteins (POT1a and POT1b in rodents, POT1 in other mammals). Mouse POT1a prevents the activation of the ATR kinase and contributes to the repression of the nonhomologous end-joining path...

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Sonraí Bibleagrafaíochta
Main Authors: Kibe, Tatsuya, Osawa, Gail A., Keegan, Catherine E., de Lange, Titia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815557/
https://ncbi.nlm.nih.gov/pubmed/19995905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01498-09
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