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Stabilization of the Nitric Oxide (NO) Prodrugs and Anti-Cancer Leads, PABA/NO and Double JS-K through Incorporation into PEG-Protected Nanoparticles

[Image: see text] Here we report the stabilization of the nitric oxide (NO) prodrugs and anti-cancer lead compounds, PABA/NO (O(2)-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2-diolate) and “Double JS-K” (1,5-bis{[1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen...

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Detalhes bibliográficos
Main Authors: Kumar, Varun, Hong, Sam Y., Maciag, Anna E., Saavedra, Joseph E., Adamson, Douglas H., Prud'homme, Robert K., Keefer, Larry K., Chakrapani, Harinath
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815019/
https://ncbi.nlm.nih.gov/pubmed/20000791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900245h
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