Determination of Nutlin-3a in Murine Plasma by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)

A sensitive and precise LC-ESI-MS/MS method for determination of nutlin-3a in murine plasma using ketoconazole as an internal standard was developed and validated. Plasma nutlin-3a samples were prepared by either a simple protein precipitation (PP) for the high concentration range (10 – 20,000 ng/mL...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Bai, Feng, Zhu, Fangyi, Tagen, Michael, Miller, Laura, Owens, Thandranese S., Mallari, Jeremy, Derrick, Edward, Zhang, Fan, Stewart, Clinton F.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814893/
https://ncbi.nlm.nih.gov/pubmed/19931997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2009.10.016
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares