Determination of Crenolanib in Human Serum and Cerebrospinal Fluid by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)

A LC-ESI-MS/MS method for the determination of crenolanib (CP-868,596) in human serum was developed and validated employing d(4)-CP-868,596 as an internal standard (ISTD). In addition to human serum, the method was also partially validated for crenolanib determination in human cerebrospinal fluid (C...

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Autors principals: Roberts, Michael S., Turner, David C., Owens, Thandranese S., Ramachandran, Abhijit, Wetmore, Cynthia, Throm, Stacy L., Stewart, Clinton F.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665945/
https://ncbi.nlm.nih.gov/pubmed/23644495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2013.04.002
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