تحميل...
Grb7 Upregulation Is a Molecular Adaptation to HER2 Signaling Inhibition Due to Removal of Akt-Mediated Gene Repression
The efficacy of anti-HER2 therapeutics, such as lapatinib and trastuzumab, is limited by primary and acquired resistance. Cellular adaptations that allow breast cancer cell to survive prolonged HER2 inhibition include de-repression of the transcription factor FOXO3A with consequent estrogen receptor...
محفوظ في:
المؤلفون الرئيسيون: | , , , , , , , , , , |
---|---|
التنسيق: | Artigo |
اللغة: | Inglês |
منشور في: |
Public Library of Science
2010
|
الموضوعات: | |
الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814867/ https://ncbi.nlm.nih.gov/pubmed/20126311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009024 |
الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|