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Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis

Phospholipase D (PLD)1 and PLD2, the classic mammalian members of the PLD uperfamily, have been linked over the past three decades to immune cell function and to cell biological processes required by cancer cells for metastasis. However, owing to the lack of effective small-molecule inhibitors, it h...

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Detalhes bibliográficos
Main Authors: Su, Wenjuan, Chen, Qin, Frohman, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814819/
https://ncbi.nlm.nih.gov/pubmed/19903073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.110
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