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Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis
Phospholipase D (PLD)1 and PLD2, the classic mammalian members of the PLD uperfamily, have been linked over the past three decades to immune cell function and to cell biological processes required by cancer cells for metastasis. However, owing to the lack of effective small-molecule inhibitors, it h...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814819/ https://ncbi.nlm.nih.gov/pubmed/19903073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.110 |
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