Cationic Lipid Formulations Alter the In Vivo Tropism of AAV2/9 Vector in Lung

Physicochemical properties of gene transfer vectors play an important role in both transduction efficiency and biodistribution following airway delivery. Adeno-associated virus (AAV) vectors are currently used in many gene transfer applications; however, the respiratory epithelium remains a challeng...

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Detalhes bibliográficos
Main Authors: Fein, David E, Limberis, Maria P, Maloney, Sean F, Heath, Jack M, Wilson, James M, Diamond, Scott L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814396/
https://ncbi.nlm.nih.gov/pubmed/19638960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.173
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