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NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia

Inhibition of NOTCH1 signaling with gamma-secretase inhibitors (GSIs), has been proposed a molecularly targeted therapy in T-cell acute lymphoblastic leukemia (T-ALL). However, GSIs seem to have limited antileukemic activity in human T-ALL and are associated with severe gastrointestinal toxicity res...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Real, Pedro J., Ferrando, Adolfo A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814171/
https://ncbi.nlm.nih.gov/pubmed/19357700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.75
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