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Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic tumor resulting from the malignant transformation of immature T-cell progenitors. Originally associated with a dismal prognosis, the outcome of T-ALL patients has improved remarkably over the last two decades as a result of the...

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Autores principales: Paganin, Maddalena, Ferrando, Adolfo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033461/
https://ncbi.nlm.nih.gov/pubmed/20965628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2010.09.004
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