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Self vs. non-self discrimination during CRISPR RNA-directed immunity
All immune systems must distinguish self from non-self to repel invaders without inducing autoimmunity. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci protect bacteria and archaea from invasion by phage and plasmid DNA through a genetic interference pathway1–9. CRISPR loci...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813891/ https://ncbi.nlm.nih.gov/pubmed/20072129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08703 |
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