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Invasive DNA, Chopped and in the CRISPR

In this issue of Structure, Wiedenheft et al. describe the structure and activity of Cas1, the only protein associated with all CRISPR loci. Cas1 is a metal-dependent deoxyribonuclease, consistent with a role in the adaptation phase of CRISPR immunity against invading nucleic acids.

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Detalhes bibliográficos
Main Authors: Marraffini, Luciano A., Sontheimer, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711432/
https://ncbi.nlm.nih.gov/pubmed/19523896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.05.002
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