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CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the latter is particularly important for the spread of antibiotic resistance. Clustered, regularly interspaced short palindromic repeats (CRISPR) loci confer sequence-directe...

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Detalhes bibliográficos
Main Authors: Marraffini, Luciano A., Sontheimer, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695655/
https://ncbi.nlm.nih.gov/pubmed/19095942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1165771
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