De novo assembly of human genomes with massively parallel short read sequencing

Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assembly of large g...

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Main Authors: Li, Ruiqiang, Zhu, Hongmei, Ruan, Jue, Qian, Wubin, Fang, Xiaodong, Shi, Zhongbin, Li, Yingrui, Li, Shengting, Shan, Gao, Kristiansen, Karsten, Li, Songgang, Yang, Huanming, Wang, Jian, Wang, Jun
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813482/
https://ncbi.nlm.nih.gov/pubmed/20019144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.097261.109
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