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State of the art de novo assembly of human genomes from massively parallel sequencing data

Recent studies in human genomes have demonstrated the use of de novo assemblies to identify genetic variations that are difficult for mapping-based approaches. Construction of multiple human genome assemblies is enabled by massively parallel sequencing, but a conventional bioinformatics solution is...

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Detalles Bibliográficos
Main Authors: Li, Yingrui, Hu, Yujie, Bolund, Lars, Wang, Jun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525208/
https://ncbi.nlm.nih.gov/pubmed/20511140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-4-4-271
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