A new strategy for genome assembly using short sequence reads and reduced representation libraries

We have developed a novel approach for using massively parallel short-read sequencing to generate fast and inexpensive de novo genomic assemblies comparable to those generated by capillary-based methods. The ultrashort (<100 base) sequences generated by this technology pose specific biological an...

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Bibliografiske detaljer
Main Authors: Young, Andrew L., Abaan, Hatice Ozel, Zerbino, Daniel, Mullikin, James C., Birney, Ewan, Margulies, Elliott H.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813480/
https://ncbi.nlm.nih.gov/pubmed/20123915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.097956.109
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