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Pebble and Rock Band: Heuristic Resolution of Repeats and Scaffolding in the Velvet Short-Read de Novo Assembler

BACKGROUND: Despite the short length of their reads, micro-read sequencing technologies have shown their usefulness for de novo sequencing. However, especially in eukaryotic genomes, complex repeat patterns are an obstacle to large assemblies. PRINCIPAL FINDINGS: We present a novel heuristic algorit...

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Autori principali: Zerbino, Daniel R., McEwen, Gayle K., Margulies, Elliott H., Birney, Ewan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793427/
https://ncbi.nlm.nih.gov/pubmed/20027311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008407
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