Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine

Kainate receptor antagonists have potential as therapeutic agents in a number of neuropathologies. Synthetic modification of the convulsant marine toxin neodysiherbaine A (NDH) previously yielded molecules with a diverse set of pharmacological actions on kainate receptors. Here we characterize three...

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Hauptverfasser: Lash-Van Wyhe, L. Leanne, Postila, Pekka A., Tsubone, Koichi, Sasaki, Makoto, Pentikäinen, Olli T., Sakai, Ryuichi, Swanson, Geoffrey T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813386/
https://ncbi.nlm.nih.gov/pubmed/19962997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.11.013
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